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1.
Rev. méd. Chile ; 148(3): 311-319, mar. 2020. tab
Article in Spanish | LILACS | ID: biblio-1115794

ABSTRACT

Background: In the perioperative context, a frailty evaluation scale must consider certain characteristics such as validation, execution speed, simplicity, the capacity to measure multiple dimensions and not being dependent on a cognitive or physical test that could not be performed prior to surgery. The test should select patients that could benefit from interventions aimed to improve their postoperative outcomes. Aim: To validate two frailty evaluation scales for the perioperative period. Material and Methods: The Risk Analysis Index with local modifications (RAI-M) were applied to 201 patients aged 73 ± 7 years (49% women) and the Edmonton frailty scale were applied in 151 patients aged 73 ± 7 years (49% women) in the preoperative period. Their results were compared with the Rockwood frailty index. Results: The Edmonton frail scale showed adequate psychometric properties and assessed multiple dimensions through 8 of the 11 original questions, achieving a discrimination power over 80% compared to the Rockwood Index. The RAI- M, demonstrated solid psychometric properties with a tool that examines 4 dimensions of frailty through 15 questions and reviewing the presence of 11 medical comorbidities. This scale had a discrimination power greater than 85% and it was significantly associated with prolongation of the planned hospital stay and mortality. Conclusions: RAI-M is a short and easily administered scale, useful to detect frailty in the preoperative period.


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Frailty , Postoperative Complications , Geriatric Assessment , Frail Elderly , Risk Assessment , Preoperative Period
2.
Arq. bras. med. nav ; 52(2): 71-94, maio-ago. 1990. ilus, tab
Article in Portuguese | LILACS | ID: lil-126063

ABSTRACT

O uso de medicamentos ototóxicos produziu inúmeros deficientes auditivos. Os efeitos colaterais atingem o ouvido interno além de outros órgäos, principalmente o rim säo antibióticos, diuréticos e substâncias usadas como armas no combate a várias doenças. Os otorrinolaringologistas devema alertar seus colegas médicos sobre os riscos da ototoxicidade. Deveriam ainda estar aptos a avaliar e acompanhar os pacientes que tiveram comcprometimento do ouvido interno durante ou após a terapia. O presente trabalho apresenta uma sumária revisäo sobre o tema, seus aspectos clínicos, patologia e tratamento. Tem como objetivo salientar importantes aspectos de interesse do especialista e do médico generalista. Destaca, à luz dos recentes avanços da farmacologia e à partir da melhor compreensäo da histofisiologia do ouvido interno, com o advento da microscopia eletrônica, as alteraçöes histopatológicas presentes no fenômeno da ototoxicidade


Subject(s)
Humans , Female , Pregnancy , Male , Adult , Child , Diuretics/adverse effects , Ear Diseases/chemically induced , Anti-Bacterial Agents/adverse effects , Drug Monitoring , Ear Diseases/pathology , Ear Diseases/physiopathology , Ear Diseases/therapy , Ear, Inner/anatomy & histology , Ear, Inner/physiology
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